Intraperitoneal pyrophosphate treatment reduces renal calcifications in Npt2a null mice
Fig 3
Urinary pyrophosphate concentration is inversely associated with renal mineralization size in a combined bivariate linear regression analysis of all mice.
All experimental WT and mutant mice from Fig 2 (n = 28) for which urine was available were evaluated using linear regression analysis to determine the association of renal mineralization with the urine pyrophosphate concentration (U-PPi) (% calcified area = 100*calcified area/total area A and calcification size = calcified area/number of mineralization B). Data points represent values of individual animals. Results of the linear regression analysis are shown as solid line with 95% confidence interval (stippled lines), R2 and p-values.