Intraperitoneal pyrophosphate treatment reduces renal calcifications in Npt2a null mice
Fig 2
The hypomorphic Enpp1asj allele worsens renal mineralization area seen in Npt2a-/- mice on regular chow.
Histomorphometric analysis of renal mineralization (%calcified area = 100*mineralization area/tissue area, A; calcification size = mineralization area/number of calcifications, um2, B) in 10 um sections of kidneys from mice fed regular chow for 10 weeks. The data represent individual animals (closed circles) with the means±SEM, p-values shown above the lines of comparisons were calculated by one-way ANOVA using Tukey’s adjustment for multiple comparisons, no significant differences were detected between groups in panel B.