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Proteomics investigation of OSCC-specific salivary biomarkers in a Hungarian population highlights the importance of identification of population-tailored biomarkers

Fig 5

Salivary protein levels determined with ELISA.

The salivary concentration of (A) thioredoxin, (B) S100A9 protein and (C) IL-6 is indicated in case of young healthy controls (YC), age matched controls (MC) and OSCC group. In cases where significant difference was observed the p value is indicated. (D) ROC analysis of the combined effect of IL-6 and S100A9 protein.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0177282.g005