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Correlation of histopathologic characteristics to protein expression and function in malignant melanoma

Fig 4

Identified melanoma markers and pathobiological processes in tissue samples of melanoma lymph node metastases.

The graphics displays key upstream regulators found according to analysis based on DAVID and IPA evaluation. The graph displays major regulated canonical pathways and subnetworks resulting in cellular functions and molecular fingerprints providing survival advantage for malignant cells with promotion to further progression and metastasis.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0176167.g004