Correlation of histopathologic characteristics to protein expression and function in malignant melanoma
Fig 3
(A) Volcano plot showing differences in approximate protein abundance between survivors and non-survivors. T-test p-value and mean fold difference shown (protein abundance evaluated as sum of PSMs). (B) As in (A), but only significant proteins shown (p<0.05). (C) Biological relationship network (IPA) for proteins differentiating between survivors and non-survivors (shown in B), and having literature links to melanoma or metastasis. Only significant proteins shown (T-test p-value below 0.01), excluding proteins having no IPA relationships within the presented set.