Analysis of transcription factors expressed at the anterior mouse limb bud
Fig 3
Expression pattern of candidates that are anterior regulators but expanded posteriorly in Shh-KO mouse limb buds.
Whole-mount in situ analysis was performed upon limbs of Shh-KO embryos (E10.5–11.5). Disruption of Shh resulted in posteriorly expanded expression of candidates in the developing limb bud (Control: WT or Shh +/-; FL: Forelimb; HL: Hind limb; A: Anterior; P: Posterior).