Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway
Fig 4
Cudraflavone C inhibits AKT phosphorylation in Caco-2 and KM12 cells.
Caco-2 and KM12 cells were exposed to either DMSO (1%) or Cud C at 10 μM for 12, 24, 48 and 72hours. Protein lysates were subjected to SDS-PAGE. GAPDH was used as loading control. Numbers displayed below each blot denote the ratio of phosphorylated to total AKT.