Upregulated Expression of Transient Receptor Potential Cation Channel Subfamily V Receptors in Mucosae of Patients with Oral Squamous Cell Carcinoma and Patients with a History of Alcohol Consumption or Smoking
Fig 5
Box plot of relative levels of expression of TRPV1, 2, 3, and 4 compared by tumor grade.
Expression levels of each target gene were normalized to those of ACTB in the same sample and are expressed relative to control group expression (DDCT method; Applied Biosystems). Box plots illustrate the median, lower, and upper quartiles of TRPV1–4 expression. Whiskers were calculated using the Tukey method; filled circles represent outliers. No consistent trends or significant differences in relative levels of expression of TRPV1, 2, 3, or 4 were observed according to tumor grade of human oral SCC.