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Transcriptome Analysis Identifies Key Metabolic Changes in the Hooded Seal (Cystophora cristata) Brain in Response to Hypoxia and Reoxygenation

Fig 5

Expression levels of components of the pyruvate dehydrogenase (PDH) complex.

The RPKM values of Pdha1, Pdhx, Dlat and Dld show significant downregulation in the seal brain slices after hypoxia and hypoxia/reoxygenation (N = 3). Error bars represent standard deviations. Statistical significance was indicated by one-way ANOVA associated with Tukey's multiple comparison tests; different letters indicate statistically significant differences.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0169366.g005