A Novel Class of Small Molecule Agonists with Preference for Human over Mouse TLR4 Activation
Fig 7
Activation of cytokine gene expression by Ugi compounds in GP PBMCs.
PBMCs were isolated from three naïve GPs. TLR4 agonists were used at 1 and 0.2 μg/ml doses to stimulate GP PBMCs for 24 hrs. SNs were analyzed via GP Affymetrix QuantiGene Plex assay. Data are expressed as the means of 3 GPs at the 1 μg/ml dose of TLR4 agonist and are representative of 2 studies. Raw data are presented in S4 Fig.