Tension Recovery following Ramp-Shaped Release in High-Ca and Low-Ca Rigor Muscle Fibers: Evidence for the Dynamic State of AMADP Myosin Heads in the Absence of ATP
Fig 8
Diagrams showing possible mechanism of tension recovery following release in high-Ca rigor fibers.
(A) A myosin head, consisting of catalytic (CAD), converter (CD), and lever arm (LD) domains, extends from myosin filament to attach an actin monomer (shaded) in actin filament, while preserving its configuration at the end of power stroke. Arrow indicated direction of power stroke. (B) On application of release, myosin head is displaced in direction indicated by arrow, producing elastic drop in rigor tension. (C) After completion of release, limited degree of elastic restoration takes place in distorted myosin head, to show up as tension recovery.