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Clinical Features of Idiopathic Interstitial Pneumonia with Systemic Sclerosis-Related Autoantibody in Comparison with Interstitial Pneumonia with Systemic Sclerosis

Fig 4

Changes in forced vital capacity (FVC) during follow-up.

(A) SSc-ILD (B) ScAb-ILD (C) Regression lines were calculated by solving the linear mixed-effects model. Baseline FVC (intercept) with ScAb-ILD (mean, 2.574 L [95% CI: 2.313–2.835]) was significantly higher than that with SSc-ILD (mean, 2.191 L [95% CI: 1.974–2.407]) (p = 0.027). The declining slopes of FVC between both groups were not significantly different (SSc-ILD: mean, -0.03979 L year-1 [95% CI: -0.05449 to -0.02509]; ScAb-ILD: mean, -0.03740 L year-1 [95% CI: -0.06446 to -0.01034] (p = 0.878).

Fig 4

doi: https://doi.org/10.1371/journal.pone.0161908.g004