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Differential Expression Pattern of THBS1 and THBS2 in Lung Cancer: Clinical Outcome and a Systematic-Analysis of Microarray Databases

Fig 6

Gene ontology analysis and network construction of THBS2 coexpressed genes.

(A) Gene ontology analysis of THBS2 coexpressed genes were conducted by using the DAVID (Database for Annotation, Visualization and Integrated Discovery) bioinformatics tool. P<0.001 for the pathway enrichment of THBS2 coexpressed genes compared with Homo sapiens transcriptome background. (B) The biological interactions of THBS2 coexpressed genes were analyzed by using Metacore. Red line, negative/ inhibition effects; Green line, positive/ activation effects. Gray line, unspecified effects.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0161007.g006