Differential Expression Pattern of THBS1 and THBS2 in Lung Cancer: Clinical Outcome and a Systematic-Analysis of Microarray Databases
Fig 3
Prognosis analysis of THBS2 coexpressed genes in lung adenocarcinoma.
(A) THBS2 coexpressed gene pattern in lung adenocarcinoma (Landi lung dataset). (B) 9 genes (CHI3L1, COL11A1, COL5A2, CYP1B1, FAP, MXRA5, THY1, VCAM1 and VCAN) were consistently identified as top 5% genes by co-expression score with Oncomine in lung AC datasets. (C) Kaplan-Meier survival curve (Kaplan-Meier plotter) showing the association of CHI3L1, COL11A1, COL5A2, FAP, MXRA5, THY1 and VCAN with progression-free survival in lung AC. (D) Kaplan-Meier survival curve showing the progression-free survival in lung AC with both high THBS2 and CYP1B1 expression, or both low THBS2 and CYP1B1 expression. AC, adenocarcinoma.