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Genome-Wide Prediction and Analysis of 3D-Domain Swapped Proteins in the Human Genome from Sequence Information

Fig 5

Case study on three different proteins of known structures.

The blue circle shows that these are experimentally known hinge regions (shown in red in left) that agree with our predictions. (A) Ribonuclease, Seminal (PDB code: 11BA), (B) Promyelocytic leukemia Zinc finger protein PLZF (PDB code: 1BUO) and (C) SH3 Domain (PDB code: 1AOJ). Complete list is provided in S3 Table.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0159627.g005