Membrane Mediated Antimicrobial and Antitumor Activity of Cathelicidin 6: Structural Insights from Molecular Dynamics Simulation on Multi-Microsecond Scale
Fig 4
Coarse-grained MD models illustrating interaction between BMAP27 and lipid-bilayers.
Snapshots of BMAP27 interacting with (A) DPPC model membrane during 10 μs time period, (B) DOPG model membrane during 10 μs time period, (C) TLM model membrane during 20 μs time period, and (D) LLM model membrane during 20 μs time period. The graphics are generated using VMD program. The α-helices of four different BMAP27 molecules are shown as blue, black, red and green in VDW format and their C-terminal hydrophobic residues as yellow. The lipid molecule types are represented in CPK format.