Parathyroid Hormone-Related Peptide (1-36) Enhances Beta Cell Regeneration and Increases Beta Cell Mass in a Mouse Model of Partial Pancreatectomy
Fig 3
(A,C) IPGTT, (B,D) and area under the curve (AUC) for IPGTT performed on (A,B) day 25 and (C,D) day 79. (E,G) ITT, (F,H) and AUCs for ITT performed on (E,F) day16 and (G,H) day 74, in the four groups of mice, as represented in Fig 2 for the line graphs, and in Fig 1 for the bar graphs. The day 16 and day 25 procedures were performed on the 30 day treatment groups (n = 4 mice/group), and the day 74 and day 79 procedures were performed on the 90 day treatment groups (n = 6 mice/group). Y-axis depicts fold-change in plasma glucose relative to basal (time 0) taken as 100%. There was no significant difference in the basal plasma glucose among the four groups in all experiments. Significance of * p≤0.02 versus sham-Veh and sham-PTHrP groups by ANOVA.