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miR-34 miRNAs Regulate Cellular Senescence in Type II Alveolar Epithelial Cells of Patients with Idiopathic Pulmonary Fibrosis

Fig 5

SA-βgal activity detected by flow cytometry in A549 cells overexpressing miR-34a, miR-34b, and miR-34c.

The relative percentage of cells with detectable SA-gal activity was measured in A549 cells overexpressing (A) miR-34a, (B) miR-34b, (C) miR-34c, or (D) mCherry control. Note the higher percentage of cells with SA-βgal activity in cells overexpressing miR-34a, miR-34b, or miR-34c compared to treated control cells.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0158367.g005