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A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits

Fig 5

mQTLs affect gene expression in human adipose tissue.

Significant mQTL SNP-CpG pairs where the SNP also shows significant association with gene expression in adipose tissue. The boxplots represent some identified mQTL SNPs and associations of the same loci with mRNA expression: (a) CHRNA5, (b) G6PC2, (c) GPX7, (d) RPL27A, (e) THNSL2 and (f) ZFP57. Annotations for these mQTLs are included in S1 Table.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0157776.g005