Trelagliptin (SYR-472, Zafatek), Novel Once-Weekly Treatment for Type 2 Diabetes, Inhibits Dipeptidyl Peptidase-4 (DPP-4) via a Non-Covalent Mechanism
Fig 6
Comparison of x-ray crystal structures of inhibitors bound to DPP-4.
Comparison of x-ray crystal structure of inhibitors bound to DPP-4 for alogliptin (left panel) and trelagliptin (right panel).