Ani9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2
Fig 3
Ani9, a potent inhibitor of ANO1.
A-C) Apical membrane current was measured in ANO1-expressed FRT cells. The indicated concentrations of ANO1 inhibitors, T16Ainh-A01, MONNA and Ani9 were applied 20 min prior to ANO1 activation by 100 μM ATP. D) Summary of dose responses (mean ± S.E., n = 4–6).