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Assessment of Free Radical Scavenging Activity of Dimethylglycine Sodium Salt and Its Role in Providing Protection against Lipopolysaccharide-Induced Oxidative Stress in Mice

Fig 6

Effects of DMG-Na on ROS concentrations (A) and mitochondrial membrane potential (B) in LPS-injected mice liver.

In panels A and B, the value of CS group is set to 100%. Values are mean ± SEMs (n = 10). Mean of a variable without a common letter differ, P < 0.05. Reactive oxygen species (ROS). CS, gastric intubation in mice with 0 mg DMG-Na/0.3 ml sterile saline solution for 28 days and intraperitoneal injection with 100 μg/kg body weight of sterile saline solution at 29 day; CL, gastric intubation in mice with 0 mg DMG-Na/0.3 ml sterile saline solution for 28 days and intraperitoneal injection with 100 μg/kg body weight of LPS at 29 day; DS, gastric intubation in mice with 12 mg DMG-Na/0.3 ml sterile saline solution for 28 days and intraperitoneal injection with 100 μg/kg body weight of sterile saline solution at 29 day; DL, gastric intubation in mice with 12 mg DMG-Na/0.3 ml sterile saline solution for 28 days and intraperitoneal injection with 100 μg/kg body weight of LPS at 29 day.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0155393.g006