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Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents

Fig 6

Chemical synthesis of pyrazole-based analogs.

Reagents: (i) KOtBu, BuOH, reflux, 3 h; (ii) RCOCl, THF, r.t., 1 h; (iii) RNCO, THF, 1 h.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0155209.g006