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Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents

Fig 5

Chemical synthesis of pyrimidine-based analogs.

Reagents: (i) 2,6-dimethylaniline, THF, reflux, 16 h; (ii) 2-(tributylstannyl)pyridine, Pd(PPh3), DMF, 100°C, 16 h.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0155209.g005