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Immune Inflammation and Disease Progression in Idiopathic Pulmonary Fibrosis

Fig 5

Differential inflammatory cells in slow and rapid progressors with and without acute exacerbation (AE).

Number of innate inflammatory cells (neutrophils, macrophages) and adaptive inflammatory cells (CD4+, CD8+, and B lymphocytes) in the lungs of slow and rapid progressors; subjects who developed and those who did not develop AE are considered separately. Horizontal bars represent median values, bottom and top of each box plot 25th and 75th, brackets 10th and 90th percentiles. Slow not AE: white; rapid not AE: red; AE: blue. * P<0.001 compared to slow who develop AE and rapid who do not develop AE

Fig 5

doi: https://doi.org/10.1371/journal.pone.0154516.g005