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Interleukin-1β-Targeted Vaccine Improves Glucose Control and β-Cell Function in a Diabetic KK-Ay Mouse Model

Fig 6

IL-1β targeted vaccine (1βEPP) reduces serum lipid levels in KK-Ay mice.

Serum levels of free fatty acids (A), triglycerides (B), and total cholesterol (C) were measured on day 56 after the primary immunization. Non-HDL cholesterol (D) was obtained by subtracting HDL-cholesterol from the total cholesterol. Data are shown as mean ± SEM (n = 8). Compared with the KK-Ay control mice, *p < 0.05.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0154298.g006