Endothelium-Derived 5-Methoxytryptophan Protects Endothelial Barrier Function by Blocking p38 MAPK Activation
Fig 5
5-MTP blocks p38 MAPK activation.
(A) and (B) Activation of p38, Src and ERK½ was determined in HUVECs treated with VEGF or pro-inflammatory cytokines. Upper panels show representative blots and lower panels show the densitometry of p-p38 MAPK. Error bars denote mean ± SD (n = 3). * indicates P < .05.