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Diaryl Disulfides as Novel Stabilizers of Tumor Suppressor Pdcd4

Fig 7

Conformational analysis of compounds 1, 2 and 4.

(A) A systematic approach was chosen to explore the conformational space around the three rotable bonds. (B-D) Global minimum energy conformations (left panel) and energy plots (right panel) of compounds 1 (B), 2 (C), and 4 (D).

Fig 7

doi: https://doi.org/10.1371/journal.pone.0151643.g007