Comparative Analysis of Technologies for Quantifying Extracellular Vesicles (EVs) in Clinical Cerebrospinal Fluids (CSF)
Fig 4
Comparison of EV quantification by NTA and TEM.
CSF EVs were fractionated into microvesicles (10,000×g) and exosomes (120,000×g) by differential ultracentrifugation and then analyzed by NTA and TEM. (A) Representative TEM images, scale bar = 200nm. (B) Total EV count as determined by NTA and TEM. Fold difference in particle detected between NTA and TEM is denoted.