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Comparative Analysis of Technologies for Quantifying Extracellular Vesicles (EVs) in Clinical Cerebrospinal Fluids (CSF)

Fig 2

Comparison of EV quantification by NTA and TRPS.

EVs were isolated from CSF collected from glioblastoma patients by differential centrifugation into microvesicle (10,000×g) and exosome (120,000×g) fractions, and resuspended in PBS. Isolated EVs were analyzed by NTA or TRPS. (A) Size profile of CSF exosomes determined by NTA and TRPS. (B) Size profile of CSF microvesicles determined by NTA and TRPS. (C) Comparison of EV yield by size ranges.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0149866.g002