Control of Methicillin-Resistant Staphylococcus aureus Pneumonia Utilizing TLR2 Agonist Pam3CSK4
Fig 5
Pam3CSK4 enhances mRNA expression of Fcγ receptor (FcγR) and complement receptor (CR).
KM mice were treated with Pam3CSK4 for 24 h prior to MRSA infection. After 6 h (A)and 12 h(B), the mRNA expression of FcγR(Ⅰ,Ⅲ) and CR(1,3) in lungs were performed by quantitative PCR. Data are expressed as the mean ± SEM of 3–5 mice/time from three independent experiments. Note: *P<0.05; **P<0.01 and ***P<0.001 versus normal saline-treated mice.