The Development of a Recombinant scFv Monoclonal Antibody Targeting Canine CD20 for Use in Comparative Medicine
Fig 5
Expression of CD20 protein in formalin fixed paraffin imbedded canine cancer tissue.
The indicated formalin-fixed, paraffin-embedded tissues were processed using immunohistochemistry as indicated in the materials and methods; and include representative images: (A) NCD1.2 staining in diffuse large B cell lymphoma (20x); (B) polyclonal anti-cd20 rabbit antibody staining in DLBCL (20x); (C) NCD1.2 staining in marginal zone lymphoma (20x); and (D) lack of NCD1.2 staining in peripheral T-cell lymphoma (10x); with infiltrating normal B-cells that are CD20+ highlighted by the arrow. The staining in brown highlights the position of the NCD1.2 reactive protein with nuclei stained in blue.