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Phenotyping of UGT1A1 Activity Using Raltegravir Predicts Pharmacokinetics and Toxicity of Irinotecan in FOLFIRI

Table 1

Patient characteristics.

ALP, alkaline phosphatase; ALT, alanine transaminase; AST, aspartate transaminase; wt, wild-type genotype; het, heterozygous variant genotype; var, homozygous variant genotype.

doi: https://doi.org/10.1371/journal.pone.0147681.t001