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Phenotyping of UGT1A1 Activity Using Raltegravir Predicts Pharmacokinetics and Toxicity of Irinotecan in FOLFIRI

Fig 4

Box-plot showing the association between the rate constant of formation of raltegravir glucuronide from raltegravir (K₂₃) and presence or absence of dose delay amongst the patients.

doi: https://doi.org/10.1371/journal.pone.0147681.g004