< Back to Article

Phenotyping of UGT1A1 Activity Using Raltegravir Predicts Pharmacokinetics and Toxicity of Irinotecan in FOLFIRI

Fig 3

Scatterplot and linear correlation between nadir absolute neutrophil count (ANC) and rate constant of formation of raltegravir glucuronide from raltegravir (K₂₃).

The regression equation is ANC = 129.2 + 89461.5*K23. R is 0.598 (p = 0.00158).

doi: https://doi.org/10.1371/journal.pone.0147681.g003