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Distribution of T Cells in Rainbow Trout (Oncorhynchus mykiss) Skin and Responsiveness to Viral Infection

Fig 5

Quantification of trout CD8+ cells in anterior and posterior skin regions.

Flow cytometry analysis of rainbow trout leukocytes isolated from anterior (A) and posterior (B) sections of the skin were stained with anti-CD8α mAb. For each individual tissue, FSC/SSC profiles are shown (top panels) and gates for lymphoid cells were defined. Bottom panels depict the CD8+ cells among the lymphoid gate (percentages of CD8α+ cells are shown). (C) Mean percentages of CD8α+ cells from three independent experiments are shown (n = 9 fish, mean ± SD). Asterisks indicate mean values in posterior sections significantly lower than values in anterior areas (P < 0.001).

Fig 5

doi: https://doi.org/10.1371/journal.pone.0147477.g005