Klotho and S100A8/A9 as Discriminative Markers between Pre-Renal and Intrinsic Acute Kidney Injury
Fig 5
Immunofluorescence study to demonstrate the presence of S100A8/A9-positive cells in the kidney from an acute kidney injury model.
Immunofluorescence study for neutrophils (CD15), monocytes/macrophages (CD68), and S100A8/A9-staining cells in an acute kidney injury model demonstrating that S100A8/A9, CD15, and CD69 staining were found frequently in the CDDP group which might reflect the inflammatory damage in this group. S100A8/A9 staining appeared to correlate with areas of CD15 (a) and CD68 staining (b). These findings also suggest that increased S100A8/A9 expression reflects the infiltration of inflammatory cells in intrinsic AKI. Magnification, × 400 in (a) and (b)