Placental Underperfusion in a Rat Model of Intrauterine Growth Restriction Induced by a Reduced Plasma Volume Expansion
Fig 5
Immunostaining of caspase-3 (A, B) and -9 (C, D) in placenta from control and IUGR 22-day pregnant rats.
Quantification of caspase 3 (cleaved) and 9 expression in the junctional (A, C) and labyrinth (B, D) zones. Each point represents one placenta. Global Score = (MI x Area)LOW + (MI x Area)MOD + (MI x Area)STRONG / Total Area of ROI (see Methods). (n = 6 rats/group). Representative immunostaining of cleaved caspase-3 from placenta of control rats (E). Inset: Arrow indicates brown positive stains.