Catabolism of Branched Chain Amino Acids Contributes Significantly to Synthesis of Odd-Chain and Even-Chain Fatty Acids in 3T3-L1 Adipocytes
Fig 9
Isotopomer spectral analysis (ISA) results.
(A) Estimated D(AcCoA)-values, fractional contributions to lipogenic acetyl-CoA precursor pool. (B) Estimated D(PropCoA)-values, fractional contributions to lipogenic propionyl-CoA precursor pool. (C) Estimated g(24h)-values, fractional new synthesis of each fatty acid during the 24 hr tracer experiment between days 6 and 7. (D & E) Estimated mass isotopomer labeling (M+1, M+2 and M+3) of AcCoA and PropCoA precursor pools from the various 13C-tracers used in this study.