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Pax6 Inactivation in the Adult Pancreas Reveals Ghrelin as Endocrine Cell Maturation Marker

Fig 21

Ubiquitous ablation of Pax6.

Double immunofluorescence staining of pancreatic cryosections from mice that were injected with tamoxifen at 2 months of age and analysed at 1 week post tamoxifen induction. A nearly 100% ablation of Pax6 was confirmed in the islets of ubiquitous Pax6 KO mice (c, d).

Fig 21

doi: https://doi.org/10.1371/journal.pone.0144597.g021