Anti-Tumor Activity of Yuanhuacine by Regulating AMPK/mTOR Signaling Pathway and Actin Cytoskeleton Organization in Non-Small Cell Lung Cancer Cells
Fig 6
Inhibition of tumor growth by YC in H1993 xenograft model.
(A) H1993 cells were injected s.c. into the flanks of nude mice and tumors, and were allowed to develop for 21 days. When they reached approximately 90 mm3, the indicated concentrations of YC were initiated. All study medications were given orally once daily for 21 days. Tumor sizes were monitored every 4~6 days. (B) The volume and weight of each tumor xenograft were measured at the termination of the experiment on day 21. (C) Animals in the control and treated groups were weighed every 4~6 days. The mean body weight of each group is presented.