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Anti-Tumor Activity of Yuanhuacine by Regulating AMPK/mTOR Signaling Pathway and Actin Cytoskeleton Organization in Non-Small Cell Lung Cancer Cells

Fig 4

Inhibitory effects of YC on cell migration and invasion in H1993 cells.

(A) H1993 cells were incubated in a 12-well plate for 24 h, wounded with a yellow tip, and treated with the indicated concentrations of YC. After incubation for 24 h, the cells were photographed using a phase-contrast microscope. (B) H1993 cells were treated for 48 h with the indicated concentrations of YC. The cell invasion assay was performed in a Matrigel-coated chamber system as described in Materials and Methods.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0144368.g004