Inhibition of Cell Proliferation and Growth of Pancreatic Cancer by Silencing of Carbohydrate Sulfotransferase 15 In Vitro and in a Xenograft Model
Fig 4
Effect of CS-E on PANC-1 tumor cell proliferation.
A WST-1 assay was performed using PANC-1 cell. The mean level of proliferation in PANC-1 cells without adding CS-E and HGF (white column) was expressed as a standard (1.0) and the data were shown relative to the standard as a proliferation index. The proliferation index in PANC-1 cells treated with low dose HGF (black column) did not show statistical difference in the culture system. In contrast, the proliferation index in HGF-treated PANC-1 cells significantly increased when adding CS-E (gray column). Data were expressed as mean±SD (n = 6 in each).