Pregnancy Augments G Protein Estrogen Receptor (GPER) Induced Vasodilation in Rat Uterine Arteries via the Nitric Oxide - cGMP Signaling Pathway
Fig 5
Effects of guanylate cyclase and BKCa channel inhibition on G1 vasodilation of rat uterine radial arteries.
G1 (10−7 M) was tested on radial uterine arteries in absence (Control, n = 8) vs. presence of guanylate cyclase (ODQ, 10-5M, n = 5) or BKCa channel (paxilline 10-5M, n = 5) inhibition. Vasodilation is expressed as a percentage of maximal response (max) obtained in papaverine and diltiazem. Data are reported as mean ± SEM. ***p<0.001.