Salinomycin Promotes Anoikis and Decreases the CD44+/CD24- Stem-Like Population via Inhibition of STAT3 Activation in MDA-MB-231 Cells
Fig 1
Salinomycin suppresses cell viability.
TNBC cell lines [(A) MDA-MB-231 and (B) 4T1 cells] were treated with salinomycin (0.5–10 μM) or vehicle (DMSO) for the indicated durations. Viable cells were evaluated by MTS assay. Results are expressed as mean ± SEM and were analyzed by two-way ANOVA followed by Bonferroni’s post hoc test (*p<0.05, ** p<0.01 and *** p<0.001, versus DMSO control). The experiment was independently performed three times (n = 3). Sal, salinomycin.