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Extrapolation-Based References Improve Motion and Eddy-Current Correction of High B-Value DWI Data: Application in Parkinson’s Disease Dementia

Fig 4

Illustration of the registration error between low and high b-value volumes.

The left and middle columns show FA-volumes obtained from a low and a high b-value data set, respectively, processed using the conventional motion and eddy-current correction method (C-MEC). The mismatch between the two data sets becomes apparent when the position of the corpus callosum and surrounding tracts (second, third, and fourth row) are compared to a fixed position indicated by the red line. The third column shows FA projections from high b-value data processed using the CSF-corrected extrapolation-based motion and eddy-current corrections (EB-MEC), where no apparent mismatch between the low and high b-value volumes is visible.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0141825.g004