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Calcium Ion Flow Permeates Cells through SOCs to Promote Cathode-Directed Galvanotaxis

Fig 5

Calcium Distributions and Concentrations In Control Cells and Cells Exposed to EFs.

(A) Calcium distributions in mouse fibroblasts without EFs as imaged using Fluo-4FF AM for 10 minutes. (B) Electric fields do not induce calcium gradients in cell bodies for 10 minutes or (C) 150 min. (D) EFs do not induce increased [Ca2+]i compared with controls, presented as the ratio (F:F0) for 10 minutes or (E) 150 minutes. Scale bar, 20μm.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0139865.g005