B-Cell Responses to Human Bocaviruses 1–4: New Insights from a Childhood Follow-Up Study
Fig 2
Pre-existing HBoV1 IgG reduces immune response against HBoV2 infection.
Two representative cases of PCR-verified HBoV2 infections without (child #52) or with (child #108) pre-existing HBoV1 IgG are shown. The red, blue and black data points respectively indicate whether the serum tested positive by PCR, tested negative by PCR, or was not tested by PCR. Although not shown in the graphs, both children tested negative for HBoV3- and 4-specific IgG.