Oseltamivir Population Pharmacokinetics in the Ferret: Model Application for Pharmacokinetic/Pharmacodynamic Study Design
Fig 6
Monte Carlo simulation of steady-state OC PK at a 5.08 mg/kg OP dose.
The thin solid curves are simulated PK for 100 individual ferrets, the open curves are the 10th–90th percentile, and the thick solid curve is the median OC concentration-time profile.