Oseltamivir Population Pharmacokinetics in the Ferret: Model Application for Pharmacokinetic/Pharmacodynamic Study Design
Fig 3
Diagnostic plots for the PK model from influenza-inoculated ferret data from studies 1 and 2.
Closed squares and open circles are for animals inoculated with influenza A and influenza B, respectively. Diagnostic plots include (A) predicted versus observed, (B) weighted residuals versus predicted, and (C) weighted residuals versus time since the last dose. The dashed lines are loess curves.